BDBM50241857 CHEMBL4091382
SMILES CC1CN(Cc2ccc(NC(=O)\C=C\c3cnccc3-c3cnn(C)c3)cc2)CCO1
InChI Key InChIKey=FLCVCISWDBTPRS-VMPITWQZSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50241857
Affinity DataEC50: 16nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair
Affinity DataIC50: 6.70nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair