BDBM50241900 CHEMBL4066959
SMILES Cn1cc(cn1)-c1ccncc1\C=C\C(=O)Nc1ccc(CN2CC3CC2CO3)cc1
InChI Key InChIKey=ZZZRHFQPNAABMT-QPJJXVBHSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50241900
Affinity DataIC50: 16nMAssay Description:Inhibition of kinase tracer 236 binding to full length N terminal GST-tagged human CDK8 (1 to 464 end residues) /CycC ( 1 to 283 end residues) expres...More data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inhibition of CDK8 in human SW480 cells assessed as reduction in IFN-gamma induced STAT1 phosphorylation at Ser727 residues preincubated for 2 hrs fo...More data for this Ligand-Target Pair