BDBM50242653 CHEMBL4074448
SMILES NC(=O)c1cccc(NC(=O)\C=C/C(=O)N2CCC(CC2)c2ccc(F)cc2)c1
InChI Key InChIKey=HIDGSHNRMYFZHS-HJWRWDBZSA-N
Data 6 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 6 hits for monomerid = 50242653
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of recombinant human His6-tagged PARP14 catalytic/WWE domain (1459 to 1801 residues) expressed in Escherichia coli BL21(DE3) preincubated ...More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
Mcdaniel College
Curated by ChEMBL
Mcdaniel College
Curated by ChEMBL
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of recombinant human His6-tagged PARP5a catalytic domain (1091 to 1325 residues) expressed in Escherichia coli BL21(DE3) preincubated for ...More data for this Ligand-Target Pair
Affinity DataIC50: 275nMAssay Description:Inhibition of recombinant human full length His6-tagged PARP1 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinylat...More data for this Ligand-Target Pair