BDBM50242953 CHEMBL4066749

SMILES CN[C@@H]1CCCN(C1)C(=O)c1cc(OCc2cc(C)no2)n(n1)-c1ccc(cc1)C#N

InChI Key InChIKey=PCDDJYROCNRHIW-QGZVFWFLSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50242953   

TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242953(CHEMBL4066749)
Affinity DataKd:  42nMAssay Description:Reversible inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysine-specific histone demethylase 1A(Homo sapiens (Human))
University Of Manchester

Curated by ChEMBL
LigandPNGBDBM50242953(CHEMBL4066749)
Affinity DataIC50:  340nMAssay Description:Inhibition of human recombinant N-terminal truncated LSD1 (151 to 852 residues) expressed in Escherichia coli using Histone H3(1 to 21)K4(Me1) biotin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed