BDBM50244037 3-propoxy-9H-pyrido[3,4-b]indole::CHEMBL499814

SMILES CCCOc1cc2c(cn1)[nH]c1ccccc21

InChI Key InChIKey=LPAODQAWVMEXKR-UHFFFAOYSA-N

Data  11 KI  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50244037   

TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  5.30nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha1beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  52nMAssay Description:Binding affinity to human recombinant GABAA alpha2 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGABA-A receptor; alpha-2/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  52.3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha2beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  68.8nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha3beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  69nMAssay Description:Binding affinity to human recombinant GABAA alpha3 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  590nMAssay Description:Binding affinity to human recombinant GABAA alpha5 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGABA-A receptor; alpha-5/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  591nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha5beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGABA A receptor alpha-4/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  1.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha4beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to human recombinant GABAA alpha6 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi:  1.00E+3nMAssay Description:Binding affinity to human recombinant GABAA alpha4 receptor assessed as inhibition constant incubated for 1 hrs by liquid scintillation counting anal...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Homo sapiens (Human))
University Of Wisconsin-Milwaukee

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]flunitrazepam from human recombinant GABAA alpha6beta3gamma2 receptor expressed in HEK cells by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKd:  591nMAssay Description:Binding affinity to GABAA alpha-5-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1(Homo sapiens (Human))
Moltech

Curated by ChEMBL
LigandPNGBDBM50244037(3-propoxy-9H-pyrido[3,4-b]indole | CHEMBL499814)
Affinity DataKd:  5nMAssay Description:Binding affinity to GABAA alpha-1-beta-2-gamma-2 receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed