BDBM50244121 CHEMBL517861::trans-4-(((4-tert-butylcyclohexyl)(1,5-dimethyl-1H-benzo[d]imidazol-2-yl)amino)methyl)-N-(1H-tetrazol-5-yl)benzamide

SMILES Cc1ccc2n(C)c(nc2c1)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C

InChI Key InChIKey=DLOPLEOQMLMFQP-HZCBDIJESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244121   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244121(CHEMBL517861 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  71nMAssay Description:Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244121(CHEMBL517861 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  15nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed