BDBM50244122 CHEMBL459457::trans-4-(((4-tert-butylcyclohexyl)(1-methyl-1H-benzo[d]imidazol-2-yl)amino)methyl)-N-(1H-tetrazol-5-yl)benzamide

SMILES Cn1c(nc2ccccc12)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C

InChI Key InChIKey=GVSOLJFUJAQHMA-MEMLXQNLSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244122   

TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244122(CHEMBL459457 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  55nMAssay Description:Antagonist activity against human GCGR expressed in CHO cells assessed as glucagon-induced cAMP accumulationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlucagon receptor(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50244122(CHEMBL459457 | trans-4-(((4-tert-butylcyclohexyl)(...)
Affinity DataIC50:  4nMAssay Description:Displacement of [125I]glucagon from human GCGR expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed