BDBM50244669 CHEMBL4079303

SMILES COc1ccc(c(OC)n1)-c1cc2c(c[nH]c2cc1Cl)C(O)=O

InChI Key InChIKey=JBRGOJOHEISXNB-UHFFFAOYSA-N

Data  1 Kd  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50244669   

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50244669(CHEMBL4079303)Copy SMILESCopy InChI

Affinity DataKd:  580nMAssay Description:Binding affinity to human BAP-tagged AMPK alpha1/beta1/gamma1 by SPR assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

Target5'-AMP-activated protein kinase catalytic subunit alpha-1/subunit beta-1/subunit gamma-1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL

LigandBDBM50244669(CHEMBL4079303)Copy SMILESCopy InChI

Affinity DataEC50:  1.60E+3nMAssay Description:Allosteric activation of human AMPK alpha1/beta1/gamma1 by TR-FRET assayMore data for this Ligand-Target Pair

Target InfoPDBReactome pathway
UniProtKB/SwissProt
antibodypediaantibodypediaantibodypediaGoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI