BDBM50245350 CHEMBL460944::N-Cyclohexyl-N0-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]pyridin-2-yl}urea

SMILES COc1cc2nccc(Oc3ccc(NC(=O)NC4CCCCC4)nc3)c2cc1OC

InChI Key InChIKey=ILWUKCBZAKGGQN-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50245350   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245350(CHEMBL460944 | N-Cyclohexyl-N0-{5-[(6,7-dimethoxyq...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245350(CHEMBL460944 | N-Cyclohexyl-N0-{5-[(6,7-dimethoxyq...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed