BDBM50246601 2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenylsulfonamido)acetic acid::CHEMBL472899

SMILES ONC(=O)CN(CC(O)=O)S(=O)(=O)c1ccc(Oc2ccccc2)cc1

InChI Key InChIKey=ZRAUMSIZBNBIFE-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50246601   

TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  14nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  1.53E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of human recombinant MMP2 transfected in mouse melanoma cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50: >1.86E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Abz-Ala-Gly-Leu-Ala-p-nitrobenzylamide as substrate after 15 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCollagenase 3(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMatrix metalloproteinase-16(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  11nMAssay Description:Inhibition of MMP16More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElastase(Pseudomonas aeruginosa)
Uit - The Arctic University Of Norway

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  4.60E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin using Mca-Arg-Pro-Pro-Gly-Phe-Ser-Ala-Phe-Lys-(Dnp)-OH as substrate after 1 hr by fluorescence assay...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Instituto Superior TéCnico

Curated by ChEMBL
LigandPNGBDBM50246601(2-(N-(2-(hydroxyamino)-2-oxoethyl)-4-phenoxyphenyl...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed