BDBM50248046 CHEMBL445871::N-(4-(2-(1-(2-(dimethylamino)ethyl)-1H-imidazol-4-yl)thieno[3,2-b]pyridin-7-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide
SMILES CN(C)CCn1cnc(c1)-c1cc2nccc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2s1
InChI Key InChIKey=CRQMAEDPCQSZBK-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50248046
Affinity DataIC50: 34nMAssay Description:Inhibition of GST-fused recombinant c-Met (unknown origin) catalytic domain expressed in baculovirus-infected Trichoplusia ni Hi5 cells after 30 mins...More data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Inhibition of TPR-fused Met (unknown origin) phosphorylation expressed in human 293T cells by ELISAMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Methylgene
Curated by ChEMBL
Methylgene
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of GST-fused recombinant VGFR2 (unknown origin) catalytic domain expressed in baculovirus-infected Sf9 cells after 10 mins by DELFIA assayMore data for this Ligand-Target Pair