BDBM50249892 6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluoromethoxy)phenyl]-2,3-dihydro-1H-pyrazol-4-yl}-1-phenyl-3-(trifluoromethyl)-3,5,6,7-tetrahydro-1H-indole-2,4-dione::CHEMBL449121

SMILES Cc1[nH]n(-c2ccc(OC(F)(F)F)cc2)c(=O)c1C1(C(=O)N(C2=C1C(=O)CC(C)(C)C2)c1ccccc1)C(F)(F)F

InChI Key InChIKey=XLEVMSDNWOWFNX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50249892   

TargetElongation of very long chain fatty acids protein 6(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50:  8.90nMAssay Description:Inhibition of human ELOVL6 expressed in african green monkey COS7 cells assessed as palmitoyl-CoA elongationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 3(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50:  337nMAssay Description:Inhibition of human ELOVL3 expressed in african green monkey COS7 cells assessed as stearoyl-CoA elongationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ELOVL1 expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 3(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50:  194nMAssay Description:Inhibition of mouse ELOVL3 expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ELOVL5 expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 6(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50:  31nMAssay Description:Inhibition of mouse ELOVL6 expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50249892(6,6-dimethyl-3-{5-methyl-3-oxo-2-[4-(trifluorometh...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ELOVL2 expressed in african green monkey COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed