BDBM50249974 CHEMBL4090787

SMILES Cc1onc(c1C(=O)Nc1ccc(cc1)C(C)(C)C)-c1ccccc1Cl

InChI Key InChIKey=HATXNIVSXOSRID-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50249974   

TargetHomeobox protein Nkx-2.5/Transcription factor GATA-4(Mus musculus)
University of Helsinki

Curated by ChEMBL
LigandPNGBDBM50249974(CHEMBL4090787)
Affinity DataIC50:  2.20E+4nMAssay Description:Inhibition of mouse GATA4/NKX2-5 transcriptional synergy expressed in African green monkey COS-1 cells measured after 30 hrs by dual luciferase repor...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed