BDBM50250005 CHEMBL4060191::US11208411, Compound FUR6-11
SMILES Nc1ncnc2n(CC3CCCNC3)nc(Oc3cccc(Cl)c3)c12
InChI Key InChIKey=ALFCMIDACCFSPY-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50250005
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human Src kinase domain (254 to 536 residues) expressed in Escherichia coli BL21 (DE3) using abltide as substrate pre-incubated for 10 ...More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
The Regents of The University of California
US Patent
The Regents of The University of California
US Patent
Affinity DataIC50: 73.1nMAssay Description:Full length CDPK1 was PCR amplified from a T. gondii RH cDNA library generated using the SMART cDNA synthesis kit (Clontech). The primers contained r...More data for this Ligand-Target Pair
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of California
Curated by ChEMBL
University of California
Curated by ChEMBL
Affinity DataIC50: 73nMAssay Description:Inhibition of C-terminal His-tagged full length Toxoplasma gondii CDPK1 expressed in Escherichia coli BL21 (DE3) using syntide-2 as substrate pre-inc...More data for this Ligand-Target Pair