BDBM50250218 CHEMBL4074694

SMILES COC(=O)c1ccc(O)c(NC(=O)CCOc2ccc(cc2)C(C)(C)CC(C)(C)C)c1

InChI Key InChIKey=MSPMVYHVOKSJJP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250218   

TargetMalate dehydrogenase, cytoplasmic(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250218(CHEMBL4074694)
Affinity DataIC50:  1.54E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250218(CHEMBL4074694)
Affinity DataIC50:  4.60E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed