BDBM50250245 CHEMBL4086789

SMILES CC(C)(C)CC(C)(C)c1ccc(OCC(=O)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)cc1

InChI Key InChIKey=CRZVLUCELMROJU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50250245   

TargetMalate dehydrogenase, mitochondrial(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250245(CHEMBL4086789)
Affinity DataIC50:  5.40E+3nMAssay Description:Inhibition of human MDH2 after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMalate dehydrogenase, cytoplasmic(Homo sapiens (Human))
Dongguk University

Curated by ChEMBL
LigandPNGBDBM50250245(CHEMBL4086789)
Affinity DataIC50:  4.74E+3nMAssay Description:Inhibition of human MDH1 expressed in Escherichia coli after 30 mins by oxaloacetate-dependent NADH oxidation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed