BDBM50250867 CHEMBL4103787
SMILES Cc1cc(cc2sc(nc12)N1C2CCC1CC(C2)OCc1c(onc1-c1ccccc1OC(F)(F)F)C1CC1)C(O)=O
InChI Key InChIKey=WSPLOCBXBHAPIN-UHFFFAOYSA-N
Data 2 EC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50250867
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 0.490nMAssay Description:Agonist activity at recombinant human GST-tagged FXR ligand binding domain (193 to 472 residues) expressed in baculovirus infected insect cells asses...More data for this Ligand-Target Pair
TargetBile acid receptor(Homo sapiens (Human))
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Genomics Institute of The Novartis Research Foundation
Curated by ChEMBL
Affinity DataEC50: 0.820nMAssay Description:Agonist activity at human FXR expressed in HEK293T cells assessed as BSEP promoter driven cellular transcriptional activity after 24 hrs by luciferas...More data for this Ligand-Target Pair