BDBM50251452 CHEMBL4077010

SMILES Cn1cc(-c2ccncc2)c2ccncc12

InChI Key InChIKey=TWAVZLGPPFVXAY-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50251452   

TargetNuclear factor of activated T-cells, cytoplasmic 1(Homo sapiens)
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251452(CHEMBL4077010)
Affinity DataEC50:  2.21E+3nMAssay Description:Induction of nuclear translocation of human GFP-tagged NFATc1 expressed in virus infected primary human skeletal muscle myoblasts after 3 hrs by DAPI...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen synthase kinase-3 beta(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251452(CHEMBL4077010)
Affinity DataIC50:  4.78E+3nMAssay Description:Inhibition of full-length recombinant human His-tagged GSK3B recombinant in baculovirus expression system using Alexa-Fluor tracer-236 incubated for ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Homo sapiens (Human))
Rigel Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50251452(CHEMBL4077010)
Affinity DataIC50:  89nMAssay Description:Inhibition of full-length recombinant human GST-tagged Dyrk1a expressed in baculovirus expression system using Alexa-Fluor tracer-236 incubated for 6...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed