BDBM50251945 CHEMBL4100075

SMILES CC1C\C(=C/c2nc(C)c(C)nc2C)C(=O)\C(C1)=C\c1nc(C)c(C)nc1C

InChI Key InChIKey=NLDGPZRIEQYIKL-ROUMAOROSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50251945   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50251945(CHEMBL4100075)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly preincubated with enzyme followed by GTP addition measured after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50251945(CHEMBL4100075)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed