BDBM50252034 CHEMBL4085902

SMILES COc1cc(Br)c(\C=C2/CC(C)C/C(=C\c3nc(C)c(C)nc3C)/C/2=N/O)cc1OC

InChI Key InChIKey=CPKHEFISZPLMBT-POLYYXPVSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50252034   

TargetFocal adhesion kinase 1(Homo sapiens (Human))
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50252034(CHEMBL4085902)
Affinity DataIC50:  7.80E+3nMAssay Description:Inhibition of FAK (unknown origin) assembly preincubated with enzyme followed by GTP addition measured after 20 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Wuhan University of Technology

Curated by ChEMBL
LigandPNGBDBM50252034(CHEMBL4085902)
Affinity DataIC50:  2.90E+3nMAssay Description:Inhibition of His6-tagged recombinant EGFR cytoplasmic domain (unknown origin) (645 to 1186 residues) expressed in baculovirus infected Sf-9 cells pr...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed