BDBM50252873 2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)propanoic acid::CHEMBL449296

SMILES NC(Cn1cc(Br)c(=O)[nH]c1=O)C(O)=O

InChI Key InChIKey=AEKIJKSVXKWGRJ-UHFFFAOYSA-N

Data  6 KI

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50252873   

TargetGlutamate receptor ionotropic, kainate 1(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252873(2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-...)
Affinity DataKi:  14.8nMAssay Description:Displacement of [3H]SYM2081 from rat recombinant iGluR5(Q)1b expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 1(Rattus norvegicus (Rat))
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252873(2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-...)
Affinity DataKi:  35nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR1 expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlutamate receptor 2(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252873(2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-...)
Affinity DataKi:  61nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR2(R) expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 3(RAT)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252873(2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-...)
Affinity DataKi:  434nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR3 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor 4(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252873(2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-...)
Affinity DataKi:  656nMAssay Description:Displacement of (R,S)-[5-methyl-3H]AMPA from rat recombinant flop iGluR4 expressed in Sf9 cellsMore data for this Ligand-Target Pair
TargetGlutamate receptor ionotropic, kainate 2(Rattus norvegicus)
European Research Centre For Drug Discovery And Development (Natsyndrugs)

Curated by ChEMBL
LigandPNGBDBM50252873(2-amino-3-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-...)
Affinity DataKi: >1.00E+5nMAssay Description:Displacement of [3H]kainic acid from rat recombinant iGluR6(V,C,R) receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed