BDBM50253040 2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthieno[2,3-d]pyrimidin-4(3H)-one::CHEMBL449543

SMILES Cc1sc2nc(N)[nH]c(=O)c2c1Sc1ccc(F)cc1

InChI Key InChIKey=DJDBVVIJYBSLIT-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50253040   

TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253040(2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthien...)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253040(2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthien...)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of Escherichia coli thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Escherichia coli)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253040(2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthien...)
Affinity DataIC50:  3.20E+4nMAssay Description:Inhibition of Escherichia coli DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Toxoplasma gondii)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253040(2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthien...)
Affinity DataIC50:  48nMAssay Description:Inhibition of Toxoplasma gondii thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDihydrofolate reductase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253040(2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthien...)
Affinity DataIC50:  2.60E+3nMAssay Description:Inhibition of human recombinant DHFRMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetThymidylate synthase(Homo sapiens (Human))
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50253040(2-Amino-5-[(4-fluorophenyl)sulfanyl]-6-methylthien...)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human thymidylate synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed