BDBM50253098 (1R,2R)-5,5-Dichloro-N-(1-cyanocyclopropyl)-2-[4-[4-(methylsulfonyl)phenyl]-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl]cyclohexanecarboxamide::(1R,2R)-5,5-dichloro-N-(1-cyanocyclopropyl)-2-(4-(4-(methylsulfonyl)phenyl)-1-(2,2,2-trifluoroethyl)-1H-pyrazol-3-yl)cyclohexanecarboxamide::CHEMBL523352::MK-1256
SMILES CS(=O)(=O)c1ccc(cc1)-c1cn(CC(F)(F)F)nc1[C@@H]1CCC(Cl)(Cl)C[C@H]1C(=O)NC1(CC1)C#N
InChI Key InChIKey=DSHIORGRZXPVSN-IAGOWNOFSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50253098
TargetCathepsin K(Oryctolagus cuniculus (rabbit))
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Merck Frosst Centre For Therapeutic Research
Curated by ChEMBL
Affinity DataIC50: 6.10nMAssay Description:Inhibition of rabbit cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of human Cathepsin KMore data for this Ligand-Target Pair
Affinity DataIC50: 0.620nMAssay Description:Inhibition of humanized rabbit cathepsin KMore data for this Ligand-Target Pair