BDBM50253154 CHEMBL492265::N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-phthalazinyl)benzamide::N-cyclopropyl-4-methyl-3-[1-(2-methylphenyl)phthalazin-6-yl]benzamide

SMILES Cc1ccccc1-c1nncc2cc(ccc12)-c1cc(ccc1C)C(=O)NC1CC1

InChI Key InChIKey=GQXMJOSCBRZMKE-UHFFFAOYSA-N

Data  1 KI  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50253154   

TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 2.94E+3nMAssay Description:Inhibition of cKitMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 5.52E+3nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 6.63E+3nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataIC50: 0.800nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50253154(N-Cyclopropyl-4-methyl-3-(1-(2-methylphenyl)-6-pht...)
Affinity DataKi:  0.400nMAssay Description:Inhibition of P38alpha MAPK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMed