BDBM50254184 CHEMBL4082366

SMILES CC(C)(O)CC(=O)N1CCC(CC1)c1ccc(NC(=O)N2Cc3ccccc3C2)cc1

InChI Key InChIKey=GBPFJQPCQMDAAN-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50254184   

TargetNicotinamide phosphoribosyltransferase(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254184(CHEMBL4082366)
Affinity DataKi:  5.60nMAssay Description:Inhibition of C-terminal His-tagged human recombinant NAMPT using FK866 or isoindoline urea-based Oregon green (488) probe incubated for 3 hrs by TR-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254184(CHEMBL4082366)
Affinity DataIC50:  8.40E+3nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Abbvie

Curated by ChEMBL
LigandPNGBDBM50254184(CHEMBL4082366)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed