BDBM50254805 CHEMBL4093952
SMILES C[C@@H]1CC[C@H](Nc2ncc(C(N)=O)c3sc(cc23)-c2ccccc2)[C@H](C)N1
InChI Key InChIKey=RBQJVPQXONDMAS-IGCXYCKISA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 50254805
Affinity DataIC50: 12nMAssay Description:Inhibition of CHK1 (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Inhibition of human ERG expressed in CHO cells at -80 mV holding potential by patch clamp assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Astrazeneca
Curated by ChEMBL
Astrazeneca
Curated by ChEMBL
Affinity DataIC50: 8.40E+3nMAssay Description:Inhibition of CHK1 in human HT29 cells assessed as abrogation of camptothecin-induced G2/M phase arrestMore data for this Ligand-Target Pair