BDBM50255134 2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-benzimidazol-2-yl}phenoxy)ethanol::CHEMBL480425

SMILES CC1(CCCCCCC1)N1CCC(CC1)n1c(nc2ccccc12)-c1cccc(OCCO)c1

InChI Key InChIKey=LQDNZHDYOIKMCY-UHFFFAOYSA-N

Data  4 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50255134   

TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]N/OFQ from human NOP receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataKi:  9.5nMAssay Description:Displacement of [3H]DPDPE from human delta opioid receptor expressed in CHOK1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataKi:  11nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataKi:  43nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataEC50: >393nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHOK1 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNociceptin receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at human NOP receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50255134(2-(3-{1-[1-(1-Methylcyclooctyl)piperidin-4-yl]-1H-...)
Affinity DataEC50:  48nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells by [35S]GTPgammaS bindingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed