BDBM50255235 CHEMBL4078924
SMILES Cc1cccc(Cn2nc(cc2-c2ccc(O)cc2)C(=O)N2CCC(Cc3ccccc3)CC2)c1
InChI Key InChIKey=BEMNHSXPLHOLFP-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 50255235
Affinity DataKi: 412nMAssay Description:Competitive inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by Michaelis-Menten plot analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB2 receptor expressed in CHOK1 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human FAAH using AMC arachidonoylamide as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
Affinity DataIC50: 500nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins in presence of DTT by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 390nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 30 mins by colorimetric analysisMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Displacement of [3H]CP55,940 from human CB1 receptor expressed in CHOK1 cell membranes after 90 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:Inhibition of recombinant human MAGL using 4-NPA as substrate after 10 mins by HPLC analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of human ABHD6 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after 5 ...More data for this Ligand-Target Pair
TargetLysophosphatidylserine lipase ABHD12(Homo sapiens (Human))
University of Ferrara
Curated by ChEMBL
University of Ferrara
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ABHD12 expressed in HEK293 cells using 2-OG as substrate preincubated for 30 mins followed by substrate addition measured after 5...More data for this Ligand-Target Pair