BDBM50256128 (2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid::(trans)-4-methylene-2-octyl-5-oxotetrahydrofuran-3-carboxylic acid::CHEMBL449993

SMILES CCCCCCCC[C@H]1OC(=O)C(=C)[C@@H]1C(O)=O

InChI Key InChIKey=VCWLZDVWHQVAJU-NEPJUHHUSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50256128   

TargetFatty acid synthase(Rattus norvegicus)
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of Sprague-Dawley rat liver fatty acid synthaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Rattus norvegicus)
Institute Of Pharmacology & Toxicology

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  1.55E+4nMAssay Description:Inhibition of rat liver FAS by Coomassie blue stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  3.24E+4nMAssay Description:Inhibition of FASN in human A375 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Gallus gallus (Chicken))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of chicken liver FASN ketoreductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFatty acid synthase(Homo sapiens (Human))
Wayne State University

Curated by ChEMBL
LigandPNGBDBM50256128((2R,3S)-4-methylene-2-octyl-5-oxotetrahydrofuran-3...)
Affinity DataIC50:  5.90E+4nMAssay Description:Inhibition of human recombinant FASN thioesterase domainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed