BDBM50256386 6-chloro-N-(2-(2-(dimethylamino)ethoxy)-4-(1H-pyrazol-4-yl)phenyl)chroman-3-carboxamide::CHEMBL481553
SMILES CN(C)CCOc1cc(ccc1NC(=O)C1COc2ccc(Cl)cc2C1)-c1cn[nH]c1
InChI Key InChIKey=AYNMCJOEQAZMQI-UHFFFAOYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50256386
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: <6nMAssay Description:Inhibition of ROCK2 assessed as myosin light chain phosphorylation by cell-based assayMore data for this Ligand-Target Pair
TargetRho-associated protein kinase 2(Homo sapiens (Human))
The Scripps Research Institute
Curated by ChEMBL
The Scripps Research Institute
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair