BDBM50257046 (S)-benzyl 1-(4-(4-chlorophenyl)thiazol-2-ylamino)-1-oxo-6-(sulfamoylamino)hexan-2-ylcarbamate::CHEMBL475391

SMILES NS(=O)(=O)NCCCC[C@H](NC(=O)OCc1ccccc1)C(=O)Nc1nc(cs1)-c1ccc(Cl)cc1

InChI Key InChIKey=ORIBHNNMIXHHJW-IBGZPJMESA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50257046   

TargetHistone deacetylase 6(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257046((S)-benzyl 1-(4-(4-chlorophenyl)thiazol-2-ylamino)...)
Affinity DataIC50:  250nMAssay Description:Inhibition of human recombinant His-tagged HDAC6 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50257046((S)-benzyl 1-(4-(4-chlorophenyl)thiazol-2-ylamino)...)
Affinity DataIC50:  150nMAssay Description:Inhibition of human recombinant FLAG-tagged HDAC1 expressed in baculovirusMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed