BDBM50257213 CHEMBL2325016

SMILES Clc1ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2nccs2)c(c1)-c1cn[nH]c1

InChI Key InChIKey=XPZRWGQUAVWXIG-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257213   

TargetCytochrome P450 2C9(Homo sapiens (Human))
Icagen

Curated by ChEMBL
LigandPNGBDBM50257213(CHEMBL2325016)
Affinity DataIC50:  36nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50257213(CHEMBL2325016)
Affinity DataIC50:  9nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium channel protein type 9 subunit alpha(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50257213(CHEMBL2325016)
Affinity DataIC50:  31nMAssay Description:Inhibition of human NaV1.7 expressed in HEK cells assessed as half inactivation potential at -120 mV holding potential by automated patch clamp metho...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed