BDBM50257418 7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydroxy-1,1'-biphenyl-4-yl)methyl]-4H-1-benzopyran-4-one::CHEMBL521821

SMILES Oc1ccc(cc1)-c1oc2cc(O)ccc2c(=O)c1Cc1ccc(cc1)-c1ccc(O)c(O)c1

InChI Key InChIKey=RPVCRYUGYBZLQH-UHFFFAOYSA-N

Data  2 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50257418   

TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataKi:  2.23E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataKi:  2.68E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1 by mixed type inhibition assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataIC50:  1.24E+4nMAssay Description:Inhibition of human cloned LMW-PTP isoform 2 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLow molecular weight phosphotyrosine protein phosphatase(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataIC50:  7.40E+3nMAssay Description:Inhibition of human cloned LMW-PTP isoform 1 expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
University Of Modena And R.E.

Curated by ChEMBL
LigandPNGBDBM50257418(7-Hydroxy-2-(4'-hydroxyphenyl)-3-[(3'',4''-dihydro...)
Affinity DataIC50:  7.70E+3nMAssay Description:Inhibition of human cloned PTP1B expressed in Escherichia coli TB1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed