BDBM50257572 CHEMBL4075593

SMILES Fc1cc(ccc1Oc1ccnc(c1)C1CC1)-c1ccn2c(CC3CC3)nnc2c1Cl

InChI Key InChIKey=LIULOGPHLPGDQS-UHFFFAOYSA-N

Data  1 KI  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257572   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257572(CHEMBL4075593)
Affinity DataKi:  54nMAssay Description:Binding affinity to human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257572(CHEMBL4075593)
Affinity DataKd:  43nMAssay Description:Positive allosteric modulation of human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes assessed as increase in glutamate-induced...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257572(CHEMBL4075593)
Affinity DataEC50:  87nMAssay Description:Positive allosteric modulation of human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes assessed as increase in glutamate-induced...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed