BDBM50257592 CHEMBL4062535

SMILES CC(C)Nc1ccc(cc1F)-c1ccn2c(CC3CC3)nnc2c1Cl

InChI Key InChIKey=CPRAFSBECNYZNT-UHFFFAOYSA-N

Data  1 KI  1 Kd  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50257592   

TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257592(CHEMBL4062535)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257592(CHEMBL4062535)
Affinity DataKd:  20nMAssay Description:Displacement of [3H]-JNJ46281222 from human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes after 60 mins by microbeta counting a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
Leiden University

Curated by ChEMBL
LigandPNGBDBM50257592(CHEMBL4062535)
Affinity DataEC50:  224nMAssay Description:Binding affinity to human metabotropic glutamate receptor 2 expressed in CHOK1 cell membranes by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed