BDBM50261656 CHEMBL3347578

SMILES CC(C)C[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(O)=O

InChI Key InChIKey=IAOFKRFVYOFYTI-KEQPWATNSA-N

Data  2 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50261656   

TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataKd:  3.20nMAssay Description:Inhibition of p53 binding to MDM2 (unknown origin) after 30 mins by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetE3 ubiquitin-protein ligase Mdm2(Homo sapiens (Human))
University of Maryland

Curated by ChEMBL
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50:  20nMAssay Description:Tested for ability to inhibit human erythrocyte carbonic-anhydrase-II- (HCA II) catalyzed carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein Mdm4(Homo sapiens (Human))TBA
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataIC50:  40nMAssay Description:Tested for ability to inhibit human erythrocyte carbonic-anhydrase-II- (HCA II) catalyzed carbon dioxide hydrationMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein Mdm4(Homo sapiens (Human))TBA
LigandPNGBDBM50261656(CHEMBL3347578)
Affinity DataKd:  8.5nMAssay Description:Agonist activity at GPR40 (unknown origin) expressed in mouse A9 cells assessed as inositol phosphate accumulation using [myo-3H]inositol after 1 hr ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed