BDBM50262673 6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-cyclopropylmethyl-amide 3-thiazol-2-ylamide::CHEMBL478614

SMILES Cc1ccc(cc1-c1ccc(cc1)C(=O)NCC1CC1)C(=O)Nc1nccs1

InChI Key InChIKey=HIOYZPRTZOZNTQ-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262673   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262673(6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-cyclop...)
Affinity DataKi:  14nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262673(6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-cyclop...)
Affinity DataIC50:  86nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed