BDBM50262915 6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-[(3-cyano-phenyl)-amide] 3-cyclopropylamide::CHEMBL476507

SMILES Cc1ccc(cc1-c1ccc(cc1)C(=O)Nc1cccc(c1)C#N)C(=O)NC1CC1

InChI Key InChIKey=OWCVMHLOTDGPGL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50262915   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262915(6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-[(3-cy...)
Affinity DataKi:  5nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50262915(6-Methyl-biphenyl-3,4'-dicarboxylic acid 4'-[(3-cy...)
Affinity DataIC50:  33nMAssay Description:Displacement of rhodamine-green labelled (2-(6-amino-3-imino-3H-xanthen-9-yl)-5-{[({4-[4-(4-Cl-3-hydroxyphenyl)-5-(4-pyridinyl)-1H-imidazol-2yl]pheny...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed