BDBM50263044 CHEMBL476960::Voglibose

SMILES OCC(CO)N[C@H]1C[C@](O)(CO)[C@@H](O)[C@H](O)[C@H]1O

InChI Key InChIKey=FZNCGRZWXLXZSZ-CIQUZCHMSA-N

Data  33 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50263044   

TargetLysosomal alpha-glucosidase(Rattus norvegicus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  110nMAssay Description:Inhibition of rat intestinal brush border membrane maltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  160nMAssay Description:Inhibition of rat intestinal brush border membrane isomaltaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSucrase-isomaltase, intestinal(Rattus norvegicus (Rat))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  70nMAssay Description:Inhibition of rat intestinal brush border membrane sucraseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of human lysosomal alpha-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen debranching enzyme(Oryctolagus cuniculus)
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  7.00E+4nMAssay Description:Inhibition of rabbit muscle amylo-1,6-glucosidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLysosomal alpha-glucosidase(Homo sapiens (Human))
Hokuriku University

Curated by ChEMBL
LigandPNGBDBM50263044(CHEMBL476960 | Voglibose)
Affinity DataIC50:  70nMAssay Description:Inhibition of maltase in human Caco-2 cell model system after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed