BDBM50263817 5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidin-7(4H)-one::CHEMBL505210

SMILES Clc1ccc(cc1)-c1c[nH]n2c1nc(Cc1ccccc1)cc2=O

InChI Key InChIKey=FIFAUXGBTKHTIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50263817   

Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis)
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263817(5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50:  1.14E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransketolase(Homo sapiens (Human))
University Of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263817(5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of human recombinant transketolase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed