BDBM50264549 CHEMBL491243::tert-butyl 2-(2-methyl-3-oxoisoindolin-4-yl)-1H-pyrrole-1-carboxylate

SMILES CN1Cc2cccc(-c3cccn3C(=O)OC(C)(C)C)c2C1=O

InChI Key InChIKey=VVCZDXMJKPHACT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264549   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264549(CHEMBL491243 | tert-butyl 2-(2-methyl-3-oxoisoindo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264549(CHEMBL491243 | tert-butyl 2-(2-methyl-3-oxoisoindo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264549(CHEMBL491243 | tert-butyl 2-(2-methyl-3-oxoisoindo...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed