BDBM50264613 7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one::CHEMBL484678

SMILES O=C1NCc2cccc(-c3cc4cc(OCc5ccccc5)ccc4[nH]3)c12

InChI Key InChIKey=UIQCZMYFTSFLPQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50264613   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264613(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Affinity DataIC50:  1.13E+4nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264613(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CDK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAurora kinase A(Homo sapiens (Human))
Johnson & Johnson Pharmaceutical Research And Development

Curated by ChEMBL
LigandPNGBDBM50264613(7-(5-(benzyloxy)-1H-indol-2-yl)isoindolin-1-one | ...)
Affinity DataIC50:  2.12E+4nMAssay Description:Inhibition of Aurora A (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed