BDBM50265114 CHEMBL495502::N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dimethylpiperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide

SMILES C[C@H]1C[C@](CC(=O)NO)(C[C@@H](C)N1)NC(=O)c1ccc(OCc2cc(C)nc3ccccc23)cc1

InChI Key InChIKey=OBBSDCUMPDPHQF-UHFFFAOYSA-N

Data  14 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50265114   

LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  2.80nMAssay Description:Inhibition of pig TACEMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-14(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  163nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  762nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStromelysin-2(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  1.65E+3nMAssay Description:Inhibition of MMP10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-15(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of MMP15More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of ADAMTS5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNeutrophil collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  2.05E+3nMAssay Description:Inhibition of MMP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of MMP9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target72 kDa type IV collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi: >3.00E+3nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  4.60E+3nMAssay Description:Inhibition of ADAMTS4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCollagenase 3(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of MMP13More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInterstitial collagenase(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50265114(N-((2R,6S)-4-(2-(hydroxyamino)-2-oxoethyl)-2,6-dim...)
Affinity DataKi:  7.80E+3nMAssay Description:Inhibition of ADAMTS1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed