BDBM50267903 CHEMBL525204::cyclohexyl(2,2-dimethyl-4-(naphthalen-1-ylsulfonyl)piperazin-1-yl)methanone

SMILES CC1(C)CN(CCN1C(=O)C1CCCCC1)S(=O)(=O)c1cccc2ccccc12

InChI Key InChIKey=WNJDEXBWZNHXJT-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50267903   

TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267903(CHEMBL525204 | cyclohexyl(2,2-dimethyl-4-(naphthal...)
Affinity DataEC50:  0.600nMAssay Description:Inverse agonist activity at human recombinant CB1R expressed in CHO cells assessed as increase in forskolin-stimulated cAMP levelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCannabinoid receptor 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50267903(CHEMBL525204 | cyclohexyl(2,2-dimethyl-4-(naphthal...)
Affinity DataIC50:  700nMAssay Description:Displacement of [3H]CP55940 from human recombinant CB1R expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed