BDBM50268077 (S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpropan-2-ylamino)propoxy)-1H-benzo[d]imidazol-2(3H)-one::CHEMBL486278
SMILES COc1ccc(CC(C)(C)NC[C@H](O)COc2cccc3[nH]c(=O)[nH]c23)cc1
InChI Key InChIKey=PBDMWGSHTOZGOM-HNNXBMFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 17 hits for monomerid = 50268077
Affinity DataIC50: 1.30nMAssay Description:Binding affinity to beta2 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
Affinity DataIC50: 0.00130nMAssay Description:Inhibition of beta2 adrenergic receptorMore data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Binding affinity to beta-1 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataEC50: 7nMAssay Description:Binding affinity to beta3 adrenoceptorMore data for this Ligand-Target Pair
Affinity DataIC50: 61nMAssay Description:Binding affinity to serotonin transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 600nMAssay Description:Binding affinity to norepinephrine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.20E+3nMAssay Description:Binding affinity to dopamine transporterMore data for this Ligand-Target Pair
Affinity DataIC50: 1.26E+3nMAssay Description:Binding affinity to CYP2D6More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.18E+4nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 3.18E+4nMAssay Description:Binding affinity to human parathyroid calcium receptor 1 expressed in HEK293 4.0-7 cells by radioligand binding assayMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 12nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Displacement of [3H](2-(2-hydroxyphenyl)-6-methyl-5-(2-methylpropyl)-3-(2-phenylethyl)-4(3H)-pyrimidinone) from human calcium receptor expressed in h...More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of DATMore data for this Ligand-Target Pair
Affinity DataIC50: 11nMAssay Description:Antagonist activity at human calcium receptor expressed in HEK293 4.0-7 cells assessed as inhibition of intracellular calcium release by FLIPR assayMore data for this Ligand-Target Pair