BDBM50268171 CHEMBL4076840

SMILES Cc1ccc(cc1C)C(CNC(=O)c1ccc(\C=C\c2ccccc2)cc1)n1ccnc1

InChI Key InChIKey=UCZSCRJCMATYOS-MDZDMXLPSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50268171   

Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Homo sapiens (Human))
Cardiff University

Curated by ChEMBL
LigandPNGBDBM50268171(CHEMBL4076840)
Affinity DataIC50:  310nMAssay Description:Inhibition of MBP-tagged human CYP24A1 expressed Escherichia coli BL21-Gold(DE3) incubated for 25 mins in presence of Adx, AdR 1,25(OH)2D3 and NADPH ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed