BDBM50270454 CHEMBL4076483

SMILES [H][C@]1(OC(=C[C@H](O)[C@H]1NC(C)=O)C(O)=O)[C@H](O)[C@H](O)CNC(=O)CCCC

InChI Key InChIKey=XVGFMAMZJCDOSQ-HFTJKPBSSA-N

Data  1 KI  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 11 hits for monomerid = 50270454   

TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataKi:  830nMAssay Description:Non-competitive inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated with substrate for 15 mins an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-4(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of human N-terminal MBP-fused NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of human N-terminal MBP-fused NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-3(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of N-terminal MBP-fused human NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of NEU1 in HPMECMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human His6-tagged NEU1 expressed in HEK293 cells using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-2(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of N-terminal MBP-fused human NEU2 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  4.82E+3nMAssay Description:Inhibition of NEU1 in HLFMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSialidase-1(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  3.74E+3nMAssay Description:Inhibition of NEU1 in HAECMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSialidase-3(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  1.10E+5nMAssay Description:Inhibition of human N-terminal MBP-fused NEU3 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSialidase-4(Homo sapiens (Human))
University Of Alberta

Curated by ChEMBL
LigandPNGBDBM50270454(CHEMBL4076483)
Affinity DataIC50:  2.20E+5nMAssay Description:Inhibition of MBP-fused human NEU4 expressed in Escherichia coli using 4MU-NANA as substrate preincubated for 15 mins followed by substrate addition ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed