BDBM50271692 CHEMBL4126611

SMILES Oc1cccc(C[C@H](NC(=O)c2cccc(c2)C(F)(F)F)C(=O)NCC#N)c1

InChI Key InChIKey=CIPOOLZFAFCOLW-INIZCTEOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271692   

TargetProcathepsin L(Homo sapiens (Human))
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271692(CHEMBL4126611)
Affinity DataIC50:  42nMAssay Description:Inhibition of human cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins by spectroph...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetToxopain-2(Toxoplasma gondii)
University Of Michigan

Curated by ChEMBL
LigandPNGBDBM50271692(CHEMBL4126611)
Affinity DataIC50:  1.40E+3nMAssay Description:Inhibition of Toxoplasma gondii cathepsin L using Z-L-R-AMC as substrate preincubated for 5 mins followed by substrate addition measured over 5 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed