BDBM50271752 CHEMBL4128114
SMILES CS(=O)(=O)Nc1ccc(cc1)-c1cc2c(ccnc2[nH]1)-c1ccc(cc1)C(N)=O
InChI Key InChIKey=WKCUMDOOJAZCDE-UHFFFAOYSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50271752
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Mus musculus)
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 316nMAssay Description:Inhibition of CAMKK2 in mouse N39 cells assessed as decrease in AMPKalpha phosphorylation at T172 preincubated for 80 mins followed by inomycin addit...More data for this Ligand-Target Pair
Affinity DataIC50: 63nMAssay Description:Inhibition of JNK1 (unknown origin)More data for this Ligand-Target Pair
TargetCalcium/calmodulin-dependent protein kinase kinase 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 13nMAssay Description:Inhibition of full-length human GST-tagged CAMKK2 using 5FAM-AKPKGNKDYHLQTCCGSLAYRRR-amide as substrate preincubated for 30 mins followed by substrat...More data for this Ligand-Target Pair
Affinity DataIC50: 316nMAssay Description:Inhibition of INSR (unknown origin)More data for this Ligand-Target Pair
TargetInhibitor of nuclear factor kappa-B kinase subunit alpha(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of IKK1 (unknown origin)More data for this Ligand-Target Pair