BDBM50271939 CHEMBL499618::N1-(4-(2-aminopyridin-4-yloxy)-3-fluorophenyl)-N3-(4-fluorophenyl)malonamide

SMILES Nc1cc(Oc2ccc(NC(=O)CC(=O)Nc3ccc(F)cc3)cc2F)ccn1

InChI Key InChIKey=GFUOJJQVQAOAKK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271939   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50271939(CHEMBL499618 | N1-(4-(2-aminopyridin-4-yloxy)-3-fl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50271939(CHEMBL499618 | N1-(4-(2-aminopyridin-4-yloxy)-3-fl...)
Affinity DataIC50:  100nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed